autoimmune hepatitis guidelines 2019

Implementation of the ACG and AGA osteoporosis screening guidelines in inflammatory bowel disease (IBD) patients who meet the guidelines' criteriaBone health in a tertiary‐care gastroenterology and hepatology populationLow serum vitamin D levels are associated with severe histological features and poor response to therapy in patients with autoimmune hepatitisSevere vitamin D deficiency is a prognostic biomarker in autoimmune hepatitisEvolving role of vitamin D in immune‐mediated disease and its implications in autoimmune hepatitisHarmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of ObesityMetabolic syndrome: pathophysiology, management, and modulation by natural compoundsTreatment adherence—room for improvement, not only in autoimmune hepatitisTherapeutic drug monitoring of thiopurine drugs in patients with inflammatory bowel disease or autoimmune hepatitisIdentifying opportunities to improve management of autoimmune hepatitis: evaluation of drug adherence and psychosocial factorsAutoimmune hepatitis exerts a profound, negative effect on health‐related quality of life: a prospective, single‐centre studyHealth‐related quality of life, depression, and anxiety in patients with autoimmune hepatitisHealth‐related quality of life in patients with autoimmune hepatitis: a questionnaire surveyHealth‐related quality of life in children with autoimmune liver diseaseAutoimmune hepatitis in children and adolescents: effect on quality of lifeThe impact of autoimmune hepatitis and its treatment on health utilityDecreased health‐related quality of life in children and adolescents with autoimmune hepatitisPsychological stress is associated with relapse in type 1 autoimmune hepatitisOutcomes of pregnancy in women with autoimmune hepatitisFollow‐up of pregnant women with autoimmune hepatitis: the disease behavior along with maternal and fetal outcomesPregnancy in autoimmune hepatitis: outcome and risk factorsImprovement of autoimmune hepatitis during pregnancy followed by flare‐up after deliveryPreimplantation factor (PIF) orchestrates systemic antiinflammatory response by immune cells: effect on peripheral blood mononuclear cellsInsight into preimplantation factor (PIF*) mechanism for embryo protection and development: target oxidative stress and protein misfolding (PDI and HSP) through essential RIKP [corrected] binding siteACG clinical guideline: liver disease and pregnancySystematic review and meta‐analysis on the effects of thiopurines on birth outcomes from female and male patients with inflammatory bowel diseaseAzathioprine use during pregnancy: unexpected intrauterine exposure to metabolitesUpdate on the teratogenicity of maternal mycophenolate mofetilImproving the end point of corticosteroid therapy in type 1 autoimmune hepatitis to reduce the frequency of relapseComparison of daily and alternate‐day prednisone during chronic maintenance therapy: a controlled crossover studyPrednisone for chronic active liver disease: dose titration, standard dose, and combination with azathioprine comparedSafety issues in the management of autoimmune hepatitisAzathioprine metabolite measurements in the treatment of autoimmune hepatitis in pediatric patients: a preliminary reportMonitoring of azathioprine metabolites in pediatric patients with autoimmune hepatitisCharacterisation and utility of thiopurine methyltransferase and thiopurine metabolite measurements in autoimmune hepatitisOutcomes in pediatric autoimmune hepatitis and significance of azathioprine metabolitesUtility of azathioprine metabolite measurements in post‐transplant recurrent autoimmune and immune‐mediated hepatitisImproved adherence and outcomes for pediatric liver transplant recipients by using text messagingProspective analysis of nonadherence in autoimmune hepatitis: a common problemThe genomic landscape of cutaneous SCC reveals drivers and a novel azathioprine associated mutational signatureBudesonide induces remission more effectively than prednisone in a controlled trial of patients with autoimmune hepatitisBudesonide in autoimmune hepatitis: the right drug at the right time for the right patientFailure of budesonide in a pilot study of treatment‐dependent autoimmune hepatitisSide effects of budesonide in liver cirrhosis due to chronic autoimmune hepatitis: influence of hepatic metabolism versus portosystemic shunts on a patient complicated with HCCLiver fibrosis may reduce the efficacy of budesonide in the treatment of autoimmune hepatitis and overlap syndromePharmacokinetics and pharmacodynamic action of budesonide in early‐ and late‐stage primary biliary cirrhosisEfficacy and limitations of budesonide as a second‐line treatment for patients with autoimmune hepatitisBudesonide versus prednisone with azathioprine for the treatment of autoimmune hepatitis in children and adolescentsInequity of care provision and outcome disparity in autoimmune hepatitis in the United KingdomProspective survey of health and socioeconomical characteristics of 249 patients with autoimmune hepatitisMycophenolate for the treatment of autoimmune hepatitis: prospective assessment of its efficacy and safety for induction and maintenance of remission in a large cohort of treatment‐naive patientsA real‐world study focused on the long‐term efficacy of mycophenolate mofetil as first‐line treatment of autoimmune hepatitisComparison of mycophenolate mofetil with standard treatment for autoimmune hepatitis: a meta‐analysisTacrolimus: a potential new treatment for autoimmune chronic active hepatitis: results of an open‐label preliminary trialShort‐term cyclosporine induces a remission of autoimmune hepatitis in childrenCyclosporin A is a promising alternative to corticosteroids in autoimmune hepatitisTacrolimus without or with the addition of conventional immunosuppressive treatment in juvenile autoimmune hepatitisCyclosporine‐A versus prednisolone for induction of remission in auto‐immune hepatitis: interim analysis report of a randomized controlled trialLong‐term follow‐up of children and young adults with autoimmune hepatitis treated with cyclosporineFollow‐up of children with autoimmune hepatitis treated with cyclosporinePrognosis of acute severe autoimmune hepatitis (AS‐AIH): the role of corticosteroids in modifying outcomeUsefulness of corticosteroids for the treatment of severe and fulminant forms of autoimmune hepatitisCorticosteroids or not in severe acute or fulminant autoimmune hepatitis: therapeutic brinksmanship and the point beyond salvationAcute severe sutoimmune hepatitis: corticosteroids or liver transplantation?Clinical epidemiology of fulminant hepatitis in JapanEarly predictors of corticosteroid treatment failure in icteric presentations of autoimmune hepatitisAcute liver failure in Japan: definition, classification, and prediction of the outcomeFeatures reflective of early prognosis in corticosteroid‐treated severe autoimmune chronic active hepatitisRapidity of treatment response and outcome in type 1 autoimmune hepatitisSystematic review with meta‐analysis: clinical manifestations and management of autoimmune hepatitis in the elderlyAntismooth muscle and antiactin antibodies are indirect markers of histological and biochemical activity of autoimmune hepatitisHyperferritinemia and hypergammaglobulinemia predict the treatment response to standard therapy in autoimmune hepatitisAngiotensin‐converting enzyme for noninvasive assessment of liver fibrosis in autoimmune hepatitisPatient selection based on treatment duration and liver biochemistry increases success rates after treatment withdrawal in autoimmune hepatitisComplete resolution of inflammatory activity following corticosteroid treatment of HBsAg‐negative chronic active hepatitisSustained remission after corticosteroid therapy for type 1 autoimmune hepatitis: a retrospective analysisHistological features associated with relapse after corticosteroid withdrawal in type 1 autoimmune hepatitisWell‐controlled autoimmune hepatitis treatment withdrawal may be safely accomplished without liver‐biopsy guidanceLate relapse of type 1 autoimmune hepatitis after corticosteroid withdrawalReview article: permanent drug withdrawal is desirable and achievable for autoimmune hepatitisOutcome after discontinuation of immunosuppression in children with autoimmune hepatitis: a population‐based studySustained remission after corticosteroid therapy of severe hepatitis B surface antigen–negative chronic active hepatitisClinical features and prognosis of severe chronic active liver disease (CALD) after corticosteroid‐induced remissionRelapse following treatment withdrawal in patients with autoimmune chronic active hepatitisClinical significance of azathioprine metabolites for the maintenance of remission in autoimmune hepatitisRandomised controlled trial of azathioprine withdrawal in autoimmune chronic active hepatitisAzathioprine for long‐term maintenance of remission in autoimmune hepatitisStopping immunosuppressive treatment in autoimmune hepatitis (AIH): is it justified (and in whom and when)?Low‐dose corticosteroid therapy after multiple relapses of severe HBsAg‐negative chronic active hepatitisAutoimmune hepatitis type 1: safety and efficacy of prolonged medical therapyManagement of patients with difficult autoimmune hepatitisSystematic review: managing suboptimal treatment responses in autoimmune hepatitis with conventional and nonstandard drugsMycophenolate mofetil for the treatment of autoimmune hepatitis in patients refractory to standard therapyMycophenolate mofetil as rescue treatment for autoimmune liver disease in children: a 5‐year follow‐upMycophenolate mofetil in autoimmune hepatitis patients not responsive or intolerant to standard immunosuppressive therapyA single center review of the use of mycophenolate mofetil in the treatment of autoimmune hepatitisMycophenolate mofetil as second line therapy in autoimmune hepatitis?The role of mycophenolate mofetil in the management of autoimmune hepatitis and overlap syndromesMycophenolate mofetil as a rescue therapy for autoimmune hepatitis patients who are not responsive to standard therapyCyclosporine treatment of autoimmune chronic active hepatitisA case of cyclosporine‐sensitive, steroid‐resistant, autoimmune chronic active hepatitisCyclosporine in the management of corticosteroid‐resistant type I autoimmune chronic active hepatitisCyclosporin in the treatment of corticosteroid resistant autoimmune chronic active hepatitisEfficacy of cyclosporin A in children with type 2 autoimmune hepatitisSecond‐line agents in pediatric patients with autoimmune hepatitis: a systematic review and meta‐analysisEfficacy of tacrolimus in the treatment of steroid refractory autoimmune hepatitisEfficacy and safety of mycophenolate mofetil and tacrolimus as second‐line therapy for patients with autoimmune hepatitisTacrolimus and mycophenolate mofetil as second‐line therapies for pediatric patients with autoimmune hepatitisLong‐term follow‐up of patients with difficult to treat type 1 autoimmune hepatitis on tacrolimus therapyThe successful treatment of autoimmune hepatitis with 6‐mercaptopurine after failure with azathioprineEfficacy of 6‐mercaptopurine as second‐line treatment for patients with autoimmune hepatitis and azathioprine intoleranceRituximab for the treatment of patients with autoimmune hepatitis who are refractory or intolerant to standard therapyInfliximab as a rescue treatment in difficult‐to‐treat autoimmune hepatitisSystematic review with meta‐analysis: mycophenolate mofetil as a second‐line therapy for autoimmune hepatitisA systematic review and meta‐analysis of second‐line immunosuppressants for autoimmune hepatitis treatmentBeneficial response to mycophenolate mofetil by patients with autoimmune hepatitis, who have failed standard therapy, is predicted by older age and lower immunoglobulin G and INR levelsUse of tacrolimus in the treatment of autoimmune hepatitis: a single centre experienceA review of the utility of tacrolimus in the management of adults with autoimmune hepatitisTransplant immunosuppressive agents in non‐transplant chronic autoimmune hepatitis: the Canadian Association for the Study of Liver (CASL) experience with mycophenolate mofetil and tacrolimusAutoimmune hepatitis induced by infliximab in a patient with Crohn's disease with no relapse after switching to adalimumabA case of autoimmune hepatitis exacerbated by the administration of etanercept in the patient with rheumatoid arthritisRole of biologics in the development of autoimmune hepatitis: a reviewAnti‐TNFalpha treatment in children and adolescents with combined inflammatory bowel disease and autoimmune liver diseaseSuccessful treatment of refractory autoimmune hepatitis with rituximabThiopurine pharmacogenetics: clinical and molecular studies of thiopurine methyltransferaseSafety and efficacy of 6‐thioguanine as a second‐line treatment for autoimmune hepatitisBiochemical efficacy of tioguanine in autoimmune hepatitis: a retrospective review of practice in the NetherlandsPromising treatment of autoimmune hepatitis with 6‐thioguanine after adverse events on azathioprine6‐Thioguanine can cause serious liver injury in inflammatory bowel disease patientsDosing 6‐thioguanine in inflammatory bowel disease: expert‐based guidelines for daily practiceReview article: overlap syndromes and autoimmune liver diseasePrimary biliary cirrhosis with additional features of autoimmune hepatitis: response to therapy with ursodeoxycholic acidAutoimmune hepatitis overlapping with primary sclerosing cholangitis in five casesCharacterization of the overlap syndrome of primary biliary cirrhosis (PBC) and autoimmune hepatitis: evidence for it being a hepatitic form of PBC in genetically susceptible individualsClinical course and outcome of autoimmune hepatitis/primary sclerosing cholangitis overlap syndromeDiagnosis and management of primary sclerosing cholangitisAutoimmune hepatitis overlap syndromes: an evaluation of treatment response, long‐term outcome and survivalLong‐term outcomes of patients with autoimmune hepatitis managed at a nontransplant centerThe impact of ethnicity on the natural history of autoimmune hepatitisThe impact of race/ethnicity on the clinical epidemiology of autoimmune hepatitisFeatures associated with treatment failure in type 1 autoimmune hepatitis and predictive value of the model of end‐stage liver diseaseClinical features, differential diagnosis and treatment of autoimmune hepatitis in the elderlyAutoimmune hepatitis in diverse ethnic populations and geographical regionsAutoimmune hepatitis in African Americans: presenting features and response to therapyHospitalizations for autoimmune hepatitis disproportionately affect black and Latino AmericansAssociation between black race and presentation and liver‐related outcomes of patients with autoimmune hepatitisDevelopment of hepatocellular carcinoma in autoimmune hepatitis patients: a case seriesHepatocellular cancer and other malignancies in autoimmune hepatitisHepatic and extrahepatic malignancies in autoimmune hepatitis.

Report of four cases and comparison with autoimmune hepatitisDrug‐induced hepatitis with autoimmune features during minocycline therapyLong‐term minocycline use for acne in healthy adolescents can cause severe autoimmune hepatitisNitrofurantoin: another cause of drug‐induced chronic active hepatitis? Screening for concomitant autoimmune diseases can be considered in patients with AIH (particularly autoimmune thyroiditis), as AIH is associated with variou… T-cell-directed hepatocyte damage in autoimmune chronic active hepatitis. Gregorio GV, Portmann B, Reid F, et al. Liver biopsy examination discloses no inflammationBS Anand, MD is a member of the following medical societies: Robert Baldassano, MD is a member of the following medical societies: Carmen Cuffari, MD is a member of the following medical societies: Mohammad F El-Baba, MD is a member of the following medical societies: Husam H Sukerek, MD is a member of the following medical societies: (B) Plasma cell predominance in a portal inflammatory infiltrate (hematoxylin and eosin; magnification, ×600). This site needs JavaScript to work properly. In the setting of AZA intolerance, MMF is an acceptable alternative therapy to maintain remission. A 10 year follow up study of patients transplanted for autoimmune hepatitis: histological recurrence precedes clinical and biochemical recurrence. Distinctive clinical phenotype and treatment outcome of type 1 autoimmune hepatitis in the elderly.

Purpose and Scope. Tripathi D, Neuberger J. Autoimmune hepatitis and liver transplantation: indications, results, and management of recurrent disease.

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