I just completed an egg retrieval with no successful embryos. We followed our doctor’s advice for this third cycle using Gonal F 300IU + Menopur 150, and Saizen 15IU every day during stimulation (prior to this we started 5-6 days of Estrace 4mg). By way of example: at age 30Y, about one out of two human eggs will be incompetent/aneuploid while at 45Y more than nine out of ten are so afflicted.


Through SFS I will provide fertility consultations (via SKYPE) to an ever-growing number of patients (from >40 countries) with complex Reproductive Dysfunction (RD) who seek access to my input and guidance.In the past, I have limited my consultations with patients from afar to those who expressed a willingness to travel to Las Vegas for treatment by me. With an LH and HCG trigger (if I remember correctly)I started with 12 antral follicles on each ovary (the most I’ve ever had; typically being 6-8 on each).

This in turn can have a deleterious effect on egg/embryo “competency”.• Controlled Ovarian Stimulation (COS) for IVF: Selecting the ideal protocol___________________________________________________If you wish to schedule an online consultation with me, please contact my assistant (Patti Converse) by phone (800-780-7437/702-533-2691), email (concierge@SherIVF.com) or, enroll online on then home-page of my website (www.SherIVF.com). At this stage, they remain in a state of biologic perfection About four months before this particular egg's domain is selected to be the lucky ovulatory one, a chamber of fluid appears within the follicle. Other than that, no real female or male factor. Please see below:Women who (regardless of age) have diminished ovarian reserve (DOR) have a reduced potential for IVF success. The key is to trigger with no less than 10,000U of hCGu (Profasi/Novarel/Pregnyl) and if hCGr (Ovidrel) is used, to make sure that 500mcg (rather than 250mcg) is administered.

Similarly, the amount/dosage of certain fertility drugs that contain LH/hCG (e.g. Had two Ivf cycles. !Women who (regardless of age) have diminished ovarian reserve (DOR) have a reduced potential for IVF success. I also do not agree with a “Lupron trigger”, see below.Ideal egg development sets the scene for optimal egg maturation that occurs 36-42h prior to ovulation or egg retrieval. Starting a family in your late 30’s or early 40’s is very common these days. What happens to the follicle, the egg's miniature dwelling, as it's cycling through its many phases of receptivity is extremely important to the health and future quality of its residing egg. What would be your recommendation for 41 yo. The hCG “trigger also enables the egg to signal the “cumulus cells” that bind it firmly to the inner wall of the follicle (through enzymatic activity), to loosen or disperse such that the egg can detach and readily be captured at egg retrieval (ER).

I have heard some doctors suggest the injections should be started 6 weeks (in some cases 8 weeks before IVF). It is also influenced by the protocol used for controlled ovarian stimulation (COH) which by fashioning the intra-ovarian hormonal environment, profoundly impacts egg development and maturation.One of the early indications that the woman has entered the climacteric and that ovarian reserve is diminishing DOR) , is the detection of a basal blood FSH level above 9.0 MIU/ml and/ or an AMH level og <2.0ng/ml.Up until a woman reaches her mid- thirties, at best, 1:2 of her eggs will likely be chromosomally normal. An egg needs to be fertilized within 12 to 24 hours after it’s released for pregnancy to occur.

Aim to avoid foods that negatively impact egg quality, such as: -Processed foods -Trans fats-Soda-Caffeine-Alcohol-Sugar #4. The new technique of egg rejuvenation could easily become a real breakthrough in fertility treatments for women over 40 and ladies with compromised egg quality. As a woman’s ovary ages, she will have increasing … After taking a break, they sought multiple second opinions. Barren was the label that came to my mind, and panic set in. My first IVF cycle I had 22 eggs, 17 fertilized, 6 day 5-6 blasts tested, but only 1 PGS normal (which implanted, but was a blighted ovum). The sad truth is that you only need one egg to get pregnant but that egg has to … After completing my medical school academic training, I too was told I was infertile. There are no symptoms, although poor quality eggs can make it difficult to conceive and make it more likely to miscarry. But it is not the elevation in FSH or the low AMH that causes embryo “incompetence”. This treatment route was validated by a clinical study in which the ovaries of menopausal rats were transplanted into the bodies of hormonally youthful rats. In fact, many aneuploid embryos a have a perfectly normal appearance under the microscope.

It is largely the egg, rather than the sperm that determines the chromosomal integrity of the embryo and only an embryo that has a normal component of 46 chromosomes (i.e. Thirty six to forty hours prior to ovulation, a surge occurs in the release of LH by the pituitary gland. If its not because of Saizen, what type of protocol should we consider to avoid empty follicles but also maximize the benefits of HGH. What are your thoughts on a protocol as well as using omnitrope?One of the commonest questions asked by patients undergoing IVF relates to the likelihood of their eggs fertilizing and the likely “quality of their embryos.

Much of this is due to the fact that such women tend to have increased production, and/or biological activity, of LH. Would human growth hormone be advised?Whenever a patient fails to achieve a viable pregnancy following embryo transfer (ET), the first question asked is why!
We had 8 good sized follicles that were developing at 15-20mm!

My current doctor is suggesting I start thinking about donor eggs which I am doing but I am still curious about whether HGH actually helps with chromosomal abnormalities or not .

While no one can influence underlying genetics or turn back the clock on a woman’s age, any competent IVF specialist should be able to tailor the protocol for COS to meet the individual needs of the patient.___________________________________________________________My wife is using HGH (Omnitrope) for her 2nd cycle of IVF. When you first cut out sugar, you may find you experience a detox hangover.

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